HCV(wikiwiki)

ʻO ka hapa nui o nā maʻi ʻaʻohe hōʻailona ʻike ʻia i ka pae koʻikoʻi o ka maʻi, hele pū me nā pae kiʻekiʻe o ka viremia a me ka piʻi ʻana o ALT.Ua ʻike ʻia ka HCV RNA i ke koko ma mua o ka anti HCV ma hope o ka maʻi HCV koʻikoʻi.Hiki ke ʻike ʻia ka HCV RNA 2 pule ma hope o ka hoʻolaha ʻana i ka wā mua, hiki ke ʻike ʻia ka HCV core antigen 1 a 2 mau lā ma hope o ka puka ʻana o HCV RNA, a ʻaʻole hiki ke ʻike ʻia ka anti HCV a hiki i ka 8 a 12 pule, ʻo ia hoʻi, ma hope o ka maʻi HCV, aia ma kahi o 8-12 pule, hiki ke 'ike 'ia ka HCV RNA wale no, a'o ka anti HCV 'ino'ole, 'o ia ho'i, ka "window period" o ka anti HCV detection, a me ka lō'ihi o ka "window period" e pili ana i ka detection reagent (e nana i ka Papa 1). ).ʻAʻole he antibody pale ka Anti HCV, akā he hōʻailona o ka maʻi HCV.Hiki i ka 15%~40% o nā maʻi me ka maʻi HCV koʻikoʻi ke hoʻomaʻemaʻe i ka maʻi i loko o 6 mahina.I ka hoʻomaʻemaʻe ʻana i ka maʻi, haʻahaʻa loa ka pae HCV RNA i ʻike ʻole ʻia, a ʻo ka anti HCV wale nō ka maikaʻi;Eia naʻe, ʻaʻole i hoʻomaʻemaʻe ʻia ka 65% ~ 80% o nā maʻi no 6 mau mahina, i kapa ʻia ʻo ka maʻi HCV mau loa.Ke hiki mai ka ma'i hepa C ma'i, ho'omaka ka HCV RNA titer e ho'opa'a, a he kakaikahi ka ho'iho'i 'ana.Inā ʻaʻole i hoʻokō ʻia ka lāʻau antiviral maikaʻi, ʻaʻole hiki ke hoʻomaʻemaʻe wale ʻia ka HCV RNA.Ma ka hoʻomaʻamaʻa lapaʻau, ʻo ka hapa nui o nā maʻi me ka maʻi hepa C maʻi maʻi maikaʻi no ka anti HCV (nā poʻe maʻi immunosuppressed, e like me nā maʻi i loaʻa i ka maʻi HIV, nā mea hoʻololi o ke kino paʻa, nā maʻi me ka hypogammaglobulinemia a i ʻole nā ​​​​mea maʻi hemodialysis he maikaʻi ʻole no ka anti HCV), a maikaʻi paha ka HCV RNA. a maikaʻi ʻole paha (he haʻahaʻa ka pae HCV RNA ma hope o ka mālama antiviral).